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HEMOSTATIS
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General term for any process that stops bleeding
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THROMBUS
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Blood clot
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EMBOLUS
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A thrombus that is not stationary, but moves through blood vessels
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SUBSTANCES THAT PROMOTE COAGULATION
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Platelets, von Willebrand factor, activated clotting factors, and tissue thromboplastin
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SUBSTANCES THAT INHIBIT COAGULATION
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Prostacyclin, antithrombin III, and proteins C and S. tissue plasminogen activator is a natural substance that dissolves clots that are already formed.
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COAGULATION SYSTEM IS CALLED A CASCADE--WHY?
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Because each activated clotting factor serves as a catalyst that amplifies the next reaction
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FIBRIN
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A large concentration of a clot forming substance
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What is the main function of coagulation modifying drugs
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To aid the body in reversing or achieving hemostasis
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ANTICOAGULANTS
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Inhibit the action or formation of clotting factors and therefore prevent clots from forming
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ANTIPLATELET DRUGS
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Prevent platelet plugs from forming by inhibiting platelet aggregation, which can be beneficial in preventing heart attacks and strokes
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HEMORRHEOLOGIC DRUGS
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Alters platelet function without preventing them from working
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ANTIFIBRINOLYTIC DRUGS AKA HEMOSTATIC DRUGS
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They promote blood coagulation
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THROMBOLYTIC DRUGS
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Lyse (break down) clots.
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If an embolus lodges in a coronary artery it causes
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A myocardial infarction (MI)
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If an embolus obstructs a brain vessel, it causes a
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Stroke
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