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Benzodiazepines
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Depress CNS activityIndications: Sedetive, relief of agitation, tx of depression, sleep induction, skeletal muscle relaxation, anxiety relief, tx of sz disorderContra: drug allergy, narrow-angle glaucoma, pregnancySE: h/a, drowsiness, vertigo, lethargy.Caution: fall hazard in elderly pt. OD SE: somnolence, confusion, coma, dec. reflexes, hypotension, res. depression. Flumazenil is antidote
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Diazepam (Valium)
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BenzodiazepineIndication: Moderate procedural sedation, muscle relaxation. Anxiety, anticonvulsant therapy.Contra: drug allergy, narrow-angle glaucoma, pregnancySE: h/a, drowsiness, vertigo, lethargy.Preg. Cat. D
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Midazolam (Versed)
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BenzodiazepineIndication: cause amnesia and anxiolysis, sedationContra: drug allergy, narrow-angle glaucoma, pregnancySE: h/a, drowsiness, vertigo, lethargy.Preg. Cat. D
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Temazepam (Restoril)
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BenzodiazepineIndication: Sleep induction, hypnoticContra: drug allergy, narrow-angle glaucoma, pregnancySE: h/a, drowsiness, vertigo, lethargy.Preg. Cat. D
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Zaleplon (Sonata)
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Non-Benzodiazepine (Short Acting)Indication: hypnotic, sleep induction
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Zolpidem (Ambien)
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Non-Benzodiazepine (Short acting)Indication: Sleep induction, SE: sleep walking, Preg. Cat. B
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Escopiclone (Lunesta)
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Non-Benzodiazepine (long acting)Indication: sleep induction Preg. Cat. C
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Ramelteon (Rozerem)
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Non-Benzodiazepine (long acting)Indication: Sleep Induction, hypnoticContra: severe liver dysfunction, avoid in patients receiving fluvoxamine, fluconazole, or ketoconazole.Preg. Cat. C
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Barbiturates
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Indications: hypnotics, sedatives, anticonvulsants, anesthesia during surgical procedures. Contra: drug allergy, pregnancy, resp. difficulties, kidney/liver diseaseSE: drowsiness, lethargy, dizziness/hangover, paradoxal restlessness or excitment
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Pentobarbital (Nembutal)
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BarbiturateIndication:Anticonvulsant, preoperative sedative, sedative, relieves anxiety. Tx withdrawal symptoms of barbiturate dependants. SE: vasodilation, hypotension, N/V, diarrhea, constipation, drowsiness, lethargy, h/a, resp. depression, apnea, coughing, hypersensitivity reactions.
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Baclofen (Lioresal)
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Muscle RelaxantIndication: Relaxes skeletal muscleContra: hypersensitivity reaction, compromised pulmonary function, active hepatic disease, impaired myocardial function
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Cyclobenzaprine (Flexeril)
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Muscle Relaxant Indication: Relaxes skeletal muscleContra: hypersensitivity reaction, compromised pulmonary function, active hepatic disease, impaired myocardial function
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Amphetamines (Dexedrine, Adderall)
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CNS StimulantIndication: ADHD and narcolepsy (methylphenidate) ADHD (dexmethylphenidate) narcolepsy (modafinil)SE: Inc. HR and BP, angina, anxiety, insomnia, h/a tremor, GI distress, dry mouth
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Methylphenidate (Ritalin)
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AmphetamineIndication: ADHD, narcolepsySE: Inc. HR and BP, angina, anxiety, insomnia, h/a tremor, GI distress, dry mouth
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Atomoxetine (Strattera)
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Indication: ADHDSE: suicidal thinking, SE: Inc. HR and BP, angina, anxiety, insomnia, h/a tremor, GI distress, dry mouth
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