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Skin is the... organ in the body and accounts for...
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- heaviest- accounts for 16% of body weight
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Major function of skin
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- to keep the body in homeostasis
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3 layers of skin
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1) epidermis2) dermis3) subcutaneous tissue
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Appendages of skin
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- hair- nails- sebaceous glands- sweat glands
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2 types of hair
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- vellus hair- short, fine, less pigmentation- terminal hair- coarser, pigmented
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Sebaceous glands
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- present everywhere except palms/soles- produce fatty substance
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2 types of sweat glands
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- endocrine glands- help control body temp.- apocrine glands- found in axilla and groin, stimulated by emotional stress
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Common symptoms of the skin
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- hair loss- rash- growths
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Basal cell carcinoma
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- 80% of skin cancers- immature cells- resembles the basal layer of the epidermis- shiny pearly translucent papules/red macules
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Squamous cell carcinoma
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- 16% skin cancers- mature cells- resembles the spinous layer of the epidermis- crusted/scaly lesions with rough surface
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Melanoma
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- 4% skin cancers- arise from melanocytes in the epidermis- primarily found on trunk and thighs- spread rapidly (only kind that mestasticizes)
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HARMM melanoma risk model
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- History of previous melanoma- Age over 50- Regular dermatologist absent- Mole changing- Male gender
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Skin cancer risk factors
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- 50 or more common moles- freckles- UV radiation- light eye or skin color- severe blistering sunburns in childhood- family history of melanoma
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Who should get a regular skin examination by a provider?
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- people older than 50 years- people with multiple melanomas or dysplastic nervous syndrome
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ABCDE for early recognition of possible melanoma
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AssymetryBorders (irregular?)Color variation (especially blue and black mixed with white and red)Diameter (>6mm or different from others)Evolution (change in size, symptoms, morphology)
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