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The amount of energy that reactants must absorb before a chemical reaction will start; also called free energy of activation.
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Activation Energy
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The
specific portion of an enzyme that binds the substrate by means of multiple
weak interactions and that form the pocket in which catalysis occurs.
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Active Site
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The binding of a regulatory molecule to a protein at one
site that affects the function of the protein at a different site.
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Allosteric Regulation
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A
metabolic pathway that consumes energy to synthesize a complex molecule from
simpler compounds.
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Anabolic Pathway
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An
adenine-containing nucleoside triphosphate that releases free energy when its
phosphate bonds are hydrolyzed. This energy is used to drive endergonic
reactions in cells.
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ATP (Adenosine Triphosphate)
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(1)
The overall flow and transformation of energy in an organism. (2) The study of
how energy flows through organisms.
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Bioenergetics
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A
metabolic pathway that releases energy by breaking down complex molecules to
simpler compounds.
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Catabolic Pathway
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A
chemical agent that increases the rate of a reaction without being consumed by
the reaction.
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Catalyst
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Energy
available in molecules for release in a chemical reaction; a form of potential
energy.
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Chemical Energy
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An
organic molecule serving as a cofactor. Most vitamins function as these in
metabolic reactions.
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Coenzyme
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Any nonprotein molecule or ion that is required for the
proper functioning of an enzyme. Cofactors can be permanently bound to the
active site or may bind loosely with the substrate during catalysis.
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Cofactor
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A
substance that reduces the activity of an enzyme by entering the active site in
place of the substrate whose structure it mimics.
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Competitive Inhibitor
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A kind of allosteric regulation whereby a shape change in
one subunit of a protein caused by substrate binding is transmitted to all the
others, facilitating binding of subsequent substrate molecules.
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Cooperativity
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A nonspontaneous chemical reaction, in which free energy
is absorbed from the surroundings.
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Endergonic Reaction
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The capacity to cause change, especially to do work (to
move matter against an opposing force).
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Energy
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