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Movement of proteins across a bilayer from the cytosol to a topologically distinct compartment.
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Transmembrane transport
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Contents of a cell that are contained wtihin its plasma membrane but, in the case of eukaryotic cells, outside the nucleus.
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Cytoplasm
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Protein sorting signal that consists of a specific three-dimensional arrangement of atoms on the folded protein's surface.
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Signal patch
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Contents of the main compartment of the cell, excluding the nucleus and membrane-bounded compartments such as endoplasmic reticulum and mitochondria.
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Cytosol
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Movement of proteins through nuclear pore complexes between the cytosol and the nucleus.
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Gated transport
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Membrane-enclosed compartment in a eukaryotic cell that has a distinct structure, macromolecular composition, and function.
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Organelle
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Protein sorting signal that consists of a short continuous sequence of amino acids.
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Signal sequence
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Why are biological membranes selectively permeable?
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Because of the proteins located in the membrane.
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Are membrane-bound and free ribosomes structurally and functionally identical?
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Yes, they differ only in the proteins they happen to be making at a particular time.
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What do signal sequences specify?
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A particular destination in the cell.
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What is the fate of a protein with no sorting signal?
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It will remain in the cytosol.
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What organelle uses gated transport?
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Nucleus
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What organelles use transmembrane transport?
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ER, mitochondria, peroxisomes
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What organelles use vesicular transport?
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Golgi apparatus, secretory vesicles, endosomes, and lysosomes.
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