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Cards In This Set
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Mixtures of dry, finely divided drugs or chemicals intended for internal or external use.
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Powders
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Difference between Dry powder inhalers and metered dose inhalers
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- Dry powder inhalers: users have to inhale the powder; it doesn’t spray out - Metered dose inhalers: you have a propeller (aerosol systems)
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Are agglomerates of powdered materials
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Granules
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What are granules used for (2)
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- For the medicinal value of their ingredients - For pharmaceutical purposes (making of tablets)
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USP -NF Classifications of powder (5)
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1.) Very coarse2.) Coarse3.) Moderately coarse4.) Fine5.) Very fine
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What is the basis for classifing USP- NF powders
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Proportion of powders capable of passing through the opening of standardized sieves of varying dimension in a specified period of time by shaking in a mechanical sieve shaker (greater the sieve number the smaller the opening)
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T or F After the very fine particle size, there is no limit to fineness of particle size
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True
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The number of openings in the sieve per linear inch
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Mesh
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The greater the sieve number the ______the mesh
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Greater
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Particle size affects: 5
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1.) Dissolution2.) Suspendability3.) Penetrability4.) Grittiness5.) Stability
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Stokes Law relates the factors to a substance ______
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Suspendability
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T or F You may depense drugs that decompose under atmospheric conditions as fine powders (STABILITY via particle size)
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False Drugs that decompose under atmospheric conditions should not be dispensed as fine powders; protect with capsule, tablets ect
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For drugs that decompose underatmospheric conditions you can incorporate them into other dosage forms: 4
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1.) Capsule 2.) Tablets 3.) Protective foil 4.) Dispense in tight containers
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When we store antibiotics in powder form instead of liquid form for the sake of stability and incorporate liquid when the patient needs it, this is called
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Powders for reconsitution
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Generally speaking, powders are used in the finest state of subdivision that is practical in order to (2)
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1.) Get rapid drug levels when used orally or by inhalation 2.) Reduce grittiness (irritation) topically
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