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People carrying only 1 sickling gene have:
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Sickle cell traint, SCT (no symptoms)
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Polycythemia and possible causes
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An excessive or abnormal increase in the number of erythrocytes; bone marrow cancer, living at high altitude
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What is the problem with polycythemia
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The excessive RBCs causes increased viscosity, which causes blood to flow sluggishly in the body and impairs circulation
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WBCs ability to slip into and out of the blood vessels
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Diapedesis
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Ability of WBCs to locate areas of tissue damage and infection in the body by responding to certain chemicals that diffuse from damaged cells
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Positive chemotaxis
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Once the WBCs have "caught the scent," they move through tissue spaces by
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Ameboid motion
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A raised white blood cell count above the normal range.
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Leukocytosis
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Abnormally low WBC count; caused by?
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Leukopenia; commonly caused by certain drugs (corticosteroids and anticancer agents)
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A cancer of bone marrow, characterized by an abnormal proliferation of WBCs
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Leukemia
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Characteristics of granulocytes; what cell types does it include
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Granules in their cytoplasm can be stained, possess lobed nuclei; neutrophils, eosinophils, basophils
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Characteristics of agranulocytes; what cell types does it include
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Lack visible cytoplasmic granules, nuclei are spherical-oval-or kidney-shaped; lymphocytes, monocytes
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List WBCs from most to least abundant
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Neutrophils, Lymphocytes, Monocytes, Eosinophils, Basophils [never let monkeys eat bananas]
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Name that cell: multilobed nucleus with fine granules, act as phagocytes at active sites of infection
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Neutrophils
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Name that cell: histamine-containing granules, initiate inflammation
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Basophils
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Name that cell: largest of WBCs, function as macrophages, important in fighting chronic infection
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Monocytes
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