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Advanced Directive
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A written expression of a person’s wishes about medical care, especially
care during a terminal or critical illness
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Best Interest Standard
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The standard used by a proxy for medical decision making
in cases in which it is impossible to know what the incompetent person’s
beliefs and values are. Such judgments are based on what are taken to be
objective beliefs about what is good for the patient
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Principle of Autonomy Extended
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The moral principle that is sometimes cited as supporting the duty to
respect the autonomous choices of a persons even after they have ceased to be
competent
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Proxy Directive
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An advanced directive that specifies a person to serve as the surrogate
decision maker in the even the writer is unable to speak for himself or herself
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Substantive Directive
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An advanced directive that record the patient’s substantive wishes about
medical treatment, specifying treatments that are desired or refused and/or
criteria for making judgments. Usually, but not always, they are designed to
apply when the patient is terminally ill or in a permanent vegetative state.
Ventilators, chemotherapy, medically supplied nutrition and hydration, and
other means of aggressive life support are often mentioned.
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Substituted Judgment
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The standard used by a proxy for medical decision making based on an
incompetent person’s beliefs and values as they were expressed while the person
was capable of expressing them.
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Indifference Point
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In research involving randomized clinical trials, the state in which
researchers honestly do not have reason to believe that one treatment is
preferable to the others. Randomized clinical trials are normally believed to
be ethical only if investigators are at the indifference point. (Sometimes also
called clinical equipoise)
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Innovative Therapy
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Therapy sometimes used by clinicians and lay people in cases in which
standard therapy is believed to be ineffective. The purpose is to try whatever
is plausible for the benefit of the patient, not the production of
generalizable, scientific knowledge.
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Justice
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The principle that an action is morally right insofar as it treats
people in similar situation equally. Different theories of justice provide
different bases for allocation of resources justly. For example, egalitarian
justice would distribute healthcare on the basis of need
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Research
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The systematic pursuit of scientific knowledge for the purpose of
advancing science. In medicine, research interventions using human subjects may
turn out to benefit the subject, but that is not the purpose, and in ethically
acceptable research using human subjects the benefit from the research
interventions cannot be known in advance.
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Social Utility
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The principle that an action or rule is morally right
insofar as it produces as much or more net good consequences as any
alternative, taking into account the benefit and harms for all parties
affected.
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Cloning
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The asexual reproduction of an organism by taking the nucleus along with
its chromosomal material from a cell of existing creature and implanting it
into an enucleated egg cell or other cell of another creature.
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Gene Enhancement
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Genetic engineering designed to improve on the normal genetic
constitution of an individual
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Gene Therapy
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Genetic engineering designed to correct a genetically caused medical
problem
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Genetic Engineering
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Genetic Intervention that strive to overcome the effects of bad genes or
to improve the genetic constitution of an individual by removing unacceptable
genes or inserting more acceptable one
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