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Extracellular Fluid (ECF)
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The interstitial fluid, plasma, and other body fluids.
The ionic concentrations and pH of this fluid is as important as its absolute quantities.
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Intracellular Fluid (ICF)
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The cytosol.
The ionic concentrations and pH (Hydrogen ion concentration) of this fluid is as important as its absolute quantities.
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Fluid Balance
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Amount of water you gain each day is equal to the amount you lose in the environment.
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Electrolytes
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Ions released through the dissociation of inorganic compounds.
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Electrolyte balance
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The gains and losses for every electrolyte are in balance.
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Acid-Base Balance
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The production of hydrogen ions in your body is precisely offset by their loss.
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Fluid Compartments
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Examples are the ECF and ICF because they both behave as distinct entities.
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Antidiuretic Hormone (ADH)
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1. stimulates water conservation in the kidneys and reduces water loss, 2. stimulates the thirst center, prompting intake of fluids.
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Osmoreceptors
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Cells found in the hypothalamus which monitor the osmotic concentration of the ECF. (Very sensitive to subtle changes).
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Aldosterone
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Secreted by the adrenal cortex. Has a major role in determining the rate of Na+ absorption and K+ loss along the DCT and collecting system of kidneys.
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Natriuretic Peptides
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ANP and BNP. Released by cardiac muscle cells b/c of abnormal stretching of heart walls. Causes:elevated blood pressure, increased blood volume.
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Fluid Shift
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A rapid water movement between the ECF and the ICF in response to an osmotic gradient.
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Dehydration
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Water depletion. Caused when water losses exceed water gains.
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Overhydration
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Water excess. Causes: 1 ingestion of large volumes of fresh water, injection of solution, 2 inability to release excess water, 3 endocrine disorders.
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Acidosis
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When the pH of plasma falls below 7.35.
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