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Gene
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- programs the amino acid sequence of a polypeptide
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Nucleic acids
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- genes consists of DNA, which belong to the class of compounds called nucleic acids- nucleic acids are polymers made of monomers called nucleotides
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What are the two types of nucleic acids?
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- desoxyrinonucleic acid (DNA)- ribonucleic acid (RNA)
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What are the roles of DNA and RNA?
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- enable living organisms to reproduce their complex components from one generation to the next
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What does DNA do?
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- provides directions for its own replication- directs RNA synthesis and through RNA, controls protein synthesis
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What is DNA?
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- the genetic material that organisms inherit from their parents- each chromosome contains one long DNA molecule, usually carrying several hundred or more genes - when a cell reproduces itself by dividing, its DNA molecules are copied and passed along from one generation of cells to the next- encoded in the structure of DNA, is the information that programs all the cell's activities- DNA however is not directly involved in running the operations of the cell; proteins are required to implement programs
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What does RNA do?
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- each gene along a DNA molecule directs synthesis of a type of RNA called messenger RNA (mRNA)- the mRNA molecule interacts with the cell's protein-synthesizing machinery to direct production of polypeptide
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The flow of genetic information
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DNA>RNA>protein
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Ribosomes
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- the sites of protein synthesis
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What happens in eukaryotic cells?
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- ribosomes are in the cytoplasm- but DNA resides in the nucleus- mRNA conveys genetic instructions for building proteins from the nucleus to the cytoplasm
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What happens in prokaryotic cells?
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- cells lack nuclei but still use mRNA to convey a message from the DNA to ribosomes and other cellular equipment that translate the coded information into amino acid sequences
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Polynucleotide
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Nucleic acids are macromolecules that exist as polymers called polynucleotides
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Nucleotides
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- each polynucleotide consists of monomers called nucleotides- composed of three parts: 1. a nitrogen containing base 2. a five-carbon sugar 3. one or more phosphate groups
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Polynucleotide and phosphate groups
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In a polynucleotide, each monomer has only one phosphate group
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Nucleoside
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- the portion of a nucleotide without any phosphate group- nitrogenous base and a sugar
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