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Related Flashcards
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Cards In This Set
| Front | Back |
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Cessation of bleeding from a cut or
severed vessel
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Hemostasis
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Hemostasis activation leading to clot
formation uses what method
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Cascade of protein activation
cell surface assembly leading to clot
formation
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This is called so when the endothelium lining the blood vessels is damaged or removed
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Thrombosis
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First physiological response to injury:
what is created in pathology
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Hemostatic plug,
thrombi
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Hemostasis and thrombosis consists of 3 phases
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1. plug (hstasis) thrombus (thrombosis)
2. fibrin mesh (2ndary hmstasis)
3. Partl/complet bk of plu/thromb fibrinolysi
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Fibrinolysis of clot is which part of hemostasis/thrombo formation
How about platelet aggregation portion
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Forming the fibrin mesh,
Plug formation
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What is required to occur to stop bleeding in primary hemostasis
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Platelet adhesion
granule release
platelet aggregation
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Factor that stabilizes prim homostasis, by forming a link btw plt receptor site on glycoprotin__ and endothelial collagen fibers
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Willebrand factor,
glycoprotein Ib/IX
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Most potent activator of PLATELETS, what action pathway is activated?
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Thrombin
Bind to PLT surface, activate PLCBeta, hydrolize PIP, IP3:Ca, DAG/PKA plecktrin granules system
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Prim Hmstasis: activated PLT exprexx what IONIC
phospholipids
What is their main function
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Phosphatidyl SERINE
Phosphatidyl INOSITOL
accelerates activation of " X and II"
|
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Intermediate protein, is an intracellular signaling P domain
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Pleckstrin
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Factor named fletcher
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Prekallikrein
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Fitzgerlad,
Flaujeau Williams factor,
contact activation factor is whic hFactor:
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HMWK high molecular weight KININOGEN
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Prothrombin is which factor
|
II
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Tissue Factor is what factor
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III
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