Front | Back |
6 Major reasons for anemia
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Hemorrhage, nutritional deficiency,
aplastic disorders, inherited disorders, chronic renal disease,
immune issues
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General manifestations of anemia
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Weakness & syncope due to
diministed O2 carrying capacity, pallor due to low blood volume &
blood pressure, hyperbilirubinemia & jaundice, splenomegaly due
to spleen breaking down bad RBCs
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What happens in nutritional deficiency
anemia?
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Red blood cells/erythrocytes fail to
mature
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Iron deficiency anemia is also known as
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Microcytic hypochromic anemia
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In iron deficiency anemia the RBCs are
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Small and pale
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If iron is deficient...
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Hemoglobin can't be formed and RBC
production slows
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Pernicious anemia results from
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Lack of vitamin B12 or lack of enzyme
needed to transport B12
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Enzyme needed to transport B12 is
called
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Intrinsic factor
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Macrocytic/megaloblastic anemia
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Giant, immature cells resulting from
lack of B12
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Macrocytic/megaloblastic anemia is
characterized by:
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Anisocytosis and poikilocytosis
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Anisocytosis is:
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Variation in RBC size
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Poikocytosis is:
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Variation in RBC shape
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Manifestations of nutritional
deficiency anemias (7)
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Neutropenia & thrombocytopenia,
,tingling, ataxia, dementia
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Hyperbilirubinemia occurs because of
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Excessive RBC breakdown and shortage
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Neutropenia
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Low white blood cell count
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