Biology 263 Quiz 10 Genetic Disorders Flashcards

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111 cards   |   Total Attempts: 188
  

Cards In This Set

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Any substance that can cause developmental abnormalities in the embryo or fetus
Teratogen
Examples of teratogens - 5
Pharmaceuticals, alcohol/smoking/drugs, infection, radiation, maternal disease
Medications with known teratogencity - 5
Thalidomide, accutane, tetracycline, coumadin, antidepressants
Hazards of smoking during pregnancy
Placenta previa, placental abruption, low birthweight/prematurity
What happens with oxygen during smoking
Carbon monoxide binds with hemoglobin instead of oxygen
Marijuana causes
Tremors and startle reflexes in newborns
Cocaine causes
Vasoconstriction to the uterus and cocaine addiction in babies
Illnesses causing damage (STORCH) - 7
syphilis, toxoplasmosis, rubella, cytomegalovirus, herpes, measles, mumps
Radiation as teratogen
High ionizing radiation (ie gamma rays) can cause death for fetus and newborn. Lower doses cause congenital abnormalities and growth retardation and cancer.
Does UV radiation affect fetus?
No
Etiology of harm due to teratogen exposure depends on:
Timing of exposure – very early or very late is less harmful
First two weeks:
Embryo has not implanted yet and result of teratogen exposure may be minimal
Weeks 2-5:
CNS, eye, and limb buds may be affected
Weeks 4-7:
CNS, heart, eye, ear, limbs, mouth/teeth may be affected
Weeks 6-10:
CNS, heart, limbs, senses, digestive system, genitalia