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X&YDetermines a person's sex
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Sex Chromosomes
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1-22 chromosomesDo not vary between sexes
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Autosomes
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Results in gametes with too many or too few chromosomesHappens in Anaphase 1 (where homologous pairs split)
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Nondisjunction
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Graphical representation of informationParents/offspring, sex of individuals, presence/absence of some trait
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Pedigree Chart
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Gradual degradation of nervous system, causing muscle spasm and personality disordersAutosomal dominant condition
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Huntington's Disease
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Defective enzyme that can't break down phenylalanineCauses damage to nervous system and mental impairmentGene located on chromosome 12
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Phenylketonuria (PKU)
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X-linked, recessiveHeterozygote who is unaffected - carrierOnly females can carryProteins needed to form blood clots are missing or reduced
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Hemophilia
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What are ways to do prenatal diagnosis?
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Ultrasound imaging (non-invasive)AmniocentesisChorionic villi sampling
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Who discovered DNA?
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Alfred Hershey and Martha Chase
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Who discovered the structure of DNA?
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Rosalind Franklin, Maurice Wilkins, Watson, Crick
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What are the nucleotides found in DNA?
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AdenineThymineCytosineGuanine
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What is the backbone of the DNA strand?
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Sugars and phosphates
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New molecules of DNA have one strand that is "conserved" (old) and one that is newEasy to fix mistakes because of base pairing
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Semiconservative Replication
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Makes sure the right thing is going opposite (base pairing properties) until new DNA strands are completedVERY fast
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DNA Polymerase
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DNA into RNA
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Transcription
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