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T lymphocytes
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Assist the B cells in producing antibodies. destroy target cells and stimulate macrophage. A T cell does not bind to a specific antigen
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B lymphocytes
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Stimulate the production of antibodies and plama cell
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Remission
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When symptoms are reduced or absent
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Exacerbation
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When symptoms occur or increase
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Arthritis
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Inflammation of a joing
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Pharmacologic therapy
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Nonopioid medication is used for pain. Also, salicylates, NSAID, and disease-modifying antirheumatic drugs
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Exercise and acitivity
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A mild analgesic agent may be suggested before exercise for a patient starting a program
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Rheumatoid arthritis
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Autoimmune disease. More females. Pannus destroyes cartilage and erodes the bone.
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RA symptoms
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Joint pain, swelling, warmth, spongy or boggy tissue, bilateral and symmetric, joint stiffness in the morning. Immobilization for a long period may lead to contractiors. also, fever, weight loss, fatigue, lymph node enlargement
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RA diagnostic
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RBC and C4 are decreased; ANA test positive; arthrocentesis shows synovial fluid that is cloudy, milky, or dark yellow and contains leukocytes. X rays shows bony erosions and narrow joint space and should be done every 3 yrs.
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RA medical management
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Salicylates or NSAIDS. also, COX-2 (Cyclo-oxygenase) involved in the inflammatory process. Methotrexate is a standard treatment.
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Tenorrhaphy
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Suturing of a tendon
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Synovectomy
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Excision of the synovial membrane
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Arthrodesis
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Surgical fusion of the joint
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Arthroplasty
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Surgical repair and replacement of joint
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