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The immune system turns agains the host body....friendly fire
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Autoimmunity
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What % of North America is afflicted with an autoimmune disease? What fraction of them are women?
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5% with 2/3 being women
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Disease which destroys the myelin of the white matter of the brain and spinal cord
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Multiple Sclerosis
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Disease which impairs communication between nerves and skeletal muscles due to destruction of ACh receptors at neural synapses.
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Myasthenia Gravis
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Disease which prompts the thyroid gland to produce excessive amounts of thyroxine (antibodies not killing follice cells, but mimmicking TSH)
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Grave's Disease
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Symptoms are Drooping upper eyelids, difficulty swallowing and talking, generalized muscle weakness
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Myasthenia Gravis
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Symptoms are visual disturbances including blindness, problems controlling muscles (weakness, clumsiness, and ultimately paralysis), speech disturbances, urinary incontinence.
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Multiple Sclerosis
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Myeling sheaths in CNS are destroyed and reduced to nonfunctional hardened lesions called....
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Sclerosis
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What causes MS to go through cycles of remission and relapse to be typical of the disease
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The axons are undamagaed, so the slow, myelin-free axons construct extra Na+ channels to compensate, and speed up the signals. This works temporarily.
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Symptoms include, elevated metabolic rate, sweating, rapid irregular heartbeat, nervousness, bulging eyeballs
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Grave's Disease
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Mixture of dead or dying neutrophils, broken-down tissue cells, and living and dead pathogens
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Pus
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Walled off sac of pus formed by collogen fibers
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Abscess
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Tumorlike growths that contain a central region of infected macrophages surrounded by uninfected macrophages and an outer fibrous capsule..... which can break out into full blown infection when immune system is compromised
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Infectious granulomas
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What is an example of an infectious granuloma?
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Tuberculosis bacilli
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Ascaris and Schistosoma are examples of what?
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Parasitic Worms
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