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What are the classes of antihistamines? (7)
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1. alkylamines2. ethanolamines3. ethylenediamines4. phenothiazines5. piperazines6. piperidines7. miscellaneous
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Name 2
alkylamines.
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Brompheniraminechlorpheniramine
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Name 2
ethanolamines.
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Carbinoxamineclemastine
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Name 2
ethyleediamines.
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Tripelennaminepyrilamine
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Name 2 phenothiazines.
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1. methdilazinepromethazine
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Name 2 piperazines
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Cyclizinehydroxyzine
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Name 2 piperidines
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Azatadinecyproheptadine
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What is another common name for antihistamines
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H1 receptor antagonists
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Name the effects of antihistamines (3)
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1. inhibit smooth muscle constriction in blood vessels and the respiratory and GI tracts2. Decrease capillary permeability3. Decrease salivation and tear formation
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What are the indications for use of antihistamines? (6)
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1. Allergic rhinitis2. anaphylaxis3. allergic conjunctivitis4. drug allergies and pseudoallergies5. Transfusions and blood and blood products6. Dermatologic conditions
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Name three non-allergic uses of antihistamines
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1. motion sickness, nausea, vomiting2. OTC sleep aids3. OTC cold remedies
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Contraindications of antihistamines (5)
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Pregnant womannarrow angle glaucomaprostatic hypertrophystenosing peptic ulcerbladder neck obstruction
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Name the possible actions of First-Generation H1 receptor Antagonists (3)
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1. CNS Depression (therapeutic levels)2. CNS stimulation (excessive doses)3. Anticholinergic Effects
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What are the two types of antihistamines?
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1.
First-Generation H1 receptor Antagonists2. Second-Generation H1 receptor Antagonists
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Name 4 anticholinergic effects
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Dry mouthurinary retentionconstipationblurred vision
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