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How many classifications of antidysrhythmias are there?
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Four
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Class I of antidysrhythmias is:
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Sodium channel blocker (Na) ~ block cardiac Na channels. slow impulse conduction in the atria, ventricles, and His-Purkinje system
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Class II of antidysrhythmias is:
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Beta Blockers ~ effects on heart ~ SA node-reduce automaticity, AV node-slow conduction velocity, in atria and ventricles, reduce contractility
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Class III of antidysrhythmias is:
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Potassium Channel blockers (K) ~ delay repolarization
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Class IV of antidysrhythmias is:
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Calcium Channel blockers (Ca) ~ effects like beta blockers
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What are some other antidysrhytmic drugs?
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Digoxin and Adenosine
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What is an example of a Class I sodium channel blocker and what does it do?
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Quinidine, delays repolarization, anticholinergic
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What are Class IA Na channel blockers used for?
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Supraventricular dysrhythmias & Ventricular dysrhythmias
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What are some adverse effects of Na channel blockers?
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Diarrhea, cinchonism, and cardiotoxicity
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What is an example of Class IB drug and what does it do?
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Lidocaine, accelerates repolariaztion, reduces automaticity
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What are Class IB Na channel blockers used for
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Ventricular dysrhthmias
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What is an ADVERSE EFFECT of Class IB Na channel blockers?
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CNS effects
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Which Na channel blocker is not used very often?
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Flecanide
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What is Flecanide use for?
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Severe ventricular or supraventricular dysrhythmias
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What kind of pt. do NOT receive Na channel blockers, class IC?
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Those with acute MI, increases mortality
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