Front | Back |
What effects the results of your lab work?
|
Agegenderlaboratory
|
What tube do you use for CBCs?
|
Lavender topwhole unclotted blood
|
Explain the process of Erythropoeiesis
|
Liver cells sense hypoxia and release erythropoietin.Erythrocytes form from stem cells in the flat bones(stem cells have the potential to become any blood cells).
|
Stages of Erythrocyte Development |
Erythrocyte-->reticulocyte-->normobalst-->erythroblst-->proerythroblast |
Severe changes in WBCs, Plts, RBCs, usually require what
|
Bone marrow bx/ aspiration
|
What shape are erythrocytes
|
Biconcave to allow for larger surface area/ volume ratio as well as deformability to squeeze through microcirculation
|
What is the normal lifespan (in days) for an erythrocyte
|
120 days
|
Normal RBC values for adult male/ female
|
Adult Male: 4.6-6.2 million/mm3Adult Female: 4.2-5.4 million/mm3
|
Cause of decrease in RBCs
|
HemorrhageDecreased levels of components to make the cellslack of erythropoietinBone marrow suppressionHemolysis
|
Causes of Polycythemia (excess RBCs)
|
Primary (polycythemia vera)Secondary: high altitudes, Chronic obstructive lung diseasesmokersconditions with very small cellsDanger: increased viscosity and clotting
|