Front | Back |
Alpha 1 location
|
Tissue
|
Alpha 2 location
|
Nerve
|
Beta 1 location
|
Heart
|
Beta 2 location
|
Smooth muscle
|
Alpha adrenergic responses
|
Vasoconstriction & CNS stimulation
|
Beta adrenergic responses
|
Bronchial, GI, and uterine smooth muscle relaxation, glycogenolysis, cardiac stimulation
|
Dopaminergic response
|
Renal vessel dilation, causing increase blood flow here
|
Direct-acting sympathomimetics
|
Binds directly to the receptor and causes a physiologic response
|
Indirect-acting sympathomimetic
|
Causes release of catecholamine that the binds to the receptor and causes the physiologic response
|
Mixed-acting sympathomimetic
|
Directly stimulates receptor by binding to it & indirectly stimulates by causing release of catecholamine to bind to the receptor
|
Alpha adrenergic drug effect
|
Vasoconstriction of the blood vessels (causes an increase in blood pressure)
|
Positive inotropic effect
|
Increased force of contraction
|
Positive chronotropic effect
|
Increased heart rate
|
Positive dromotropic effect
|
Increased conduction through the AV node
|
Beta adrenergic drug effect
|
Bronchodilation
|