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Biological Perspective
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Emphasis on the role of biological factors on abnormal behaviour (ex. depression)
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What is the system that is most talked about with the biological perspectives?
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Nervous system
Interested in Neural transmission/ neural transmitters and their effect on behaviour
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Neuron
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A nerve cell
the basic building block of the nervous system
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Who were the biological perspectives inspired by?
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Physican from Hippocrates through Kraepelin
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DNA
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Deoxyribonucleic acid is a double strand complex molecule of helical structure that contains the genetic instructions for building and maintaining living organisisms.
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Genetics
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The study of how traits are passed down from one gen to the next and how these traits affet the way we look, function and behave
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Genome
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Comprises of ALL genetic material encoded in the DNA located in the nucleus of cells in living organisms.
Represent its essential organic compounds
A adenie
T thymine
C cytosine
G guanine
A-T
G-C determines our genetic code
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DNA in each cell =
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Bundled into 23 chromosomes
23-237 million base pairs
chromosomes contain 231-3141 genes
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How many genes is the human genome comprise of?
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20 000-25 000 genes
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Protein
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Organic compounds consisting of amino acids that perform and make up the majority of cellular structures
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General errors can also develop prenatally from exposure to _______ and __________
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Teratogens- any substances or conditions, such as drugs, X rays, infectious diseases that interfere with normal prenatal dev.
AND
Mutagens- pesticides, heavy metals, radiation that produce heritable changes in cellular DNA
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Epigenome
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The sum total of inherited and acquired molecular variations to the genome that lead to changes in gene regulation without changing the DNA sequence of the genome itself.
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Epigenetics Research
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Study of the heritable and acquired changes in gene regulation (phenotype) that occur without affecting DNA sequence (genotype)
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Epigenome plays a vital role in gene regulation through 2 key means...
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1. gene expression - the process by which a gene sequence becomes activated and is translated intot he proteins that determine the structure/ functions of body cells.
2. gene silencing - the process of preventing or suppressing (switching off) a gene sequence from being translated into proteins
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What does the epigenome also regulate?
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Hundreds of other critically precise tasks in our cells...all the ongoing functional and maintenance cellular processes by signalling a gene or polygene when to turn on or off.
tells genes when to go to work (ex. balancing bld sugar levels, controlling brain cell activity)
If it fails toregulate or signal genes to turn on/off - cancer can form
genes remain silent unless activated by epigenome
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