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What are 5 primary adrenergic agonists?
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Alpha 1 & 2 receptors and Beta 1 & 2 receptors and dopamine.
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What does Alpha 1 receptors, when activated, result in?
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Vasoconstriction and mydriasis (pupil dilation)
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What are some uses for Alpha 1 agonists?
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Homeostasis, nasal decongestant, adjunct to local anesthesia, elevation of BP, dilation of pupils
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What are some adverse effects of Alpha 1 agonists?
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HTN, necrosis around IV site, bradycardia
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What are some uses of Alpha 2 agonists?
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Activation of these receptors causes inhibition of norepinephrine (NE) release
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Side note to remembering beta 1 vs. beta 2....
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* Beta 1 (beta 1 affects heart ~ only have 1 heart)
* Beta 2 (beta 2 affects lungs ~ have 2 lungs)
*beta 2 also affects uterus*
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What can activate Beta 1 receptors?
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Epinephrine, norepinephrine, dopamine, isoproterneol, dobutamine, and ephedrine
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What are Beta 1 agonists used for?
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Cardiac arrest, heart failure, shock, AV heart block
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What are some adverse effects of Beta 1 agonists?
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Altered heart rate/rhythm and angina
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What can activate Alpha 1 agonists?
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Epinephrine, norepinephrine, phenylephrine, ephedrine, and dopamine.
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What can activate Alpha 2 agonists?
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Epinephrine, norepinephrine, and ephedrine
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What can activate Beta 2 agonists?
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Epinephrine, isoproterenol, and terbutaline
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T/F: usage of Beta 2 agonists is limited to the lungs and uterus
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TRUE
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What are some indications for Beta 2 agonist use?
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Asthma, delay pre-term labor
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What are some adverse effects of Beta 2 agonists?
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Hyperglycemia, tremor,
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